1-甲基-1H-吡唑-3,5-二甲酰氯合成路线 （共 4 条）
反应条件
1: 88 percent / 6N HCl / H2O / 4 h / Heating
2: thionyl chloride / 1 h / Heating
View Scheme
参考文献
Iturrino; Navarro; Rodriguez-Franco; Contreras; Escario; Martinez; Del Rosario Pardo
European Journal of Medicinal Chemistry, 1987 , vol. 22, # 5 p. 445 - 451
反应条件
1: 93 percent / bromine
2: 94 percent / potassium carbonate / acetone / Heating
3: 88 percent / 6N HCl / H2O / 4 h / Heating
4: thionyl chloride / 1 h / Heating
View Scheme
参考文献
Iturrino; Navarro; Rodriguez-Franco; Contreras; Escario; Martinez; Del Rosario Pardo
European Journal of Medicinal Chemistry, 1987 , vol. 22, # 5 p. 445 - 451
反应条件
1: 94 percent / potassium carbonate / acetone / Heating
2: 88 percent / 6N HCl / H2O / 4 h / Heating
3: thionyl chloride / 1 h / Heating
View Scheme
参考文献
Iturrino; Navarro; Rodriguez-Franco; Contreras; Escario; Martinez; Del Rosario Pardo
European Journal of Medicinal Chemistry, 1987 , vol. 22, # 5 p. 445 - 451
参考文献
Elguero, J.; Navarro, P.; Franco, M. I. Rodriguez
Chemistry Letters, 1984 , p. 425 - 428
