1.1: aq. NaOH / dioxane / 12 h / 20 °C 2.1: CO(Im)2; MgCl2; Et3N / tetrahydrofuran / 24 h / 20 °C 3.1: 75 percent / NaH / dimethylformamide / 3 h / 20 °C 4.1: anisole / trifluoroacetic acid / 0.5 h / 0 °C 5.1: Et3N; DMAP / benzene / 1 h / 20 °C 6.1: 71 percent / EtONa / ethanol / 1 h / Heating 7.1: 87 percent / DDQ / dioxane / 4 h / Heating 8.1: 81 percent / NaOH / ethanol / 6 h / 0 °C 9.1: ethyl chloroformate; Et3N / tetrahydrofuran / 0.5 h / 0 °C 9.2: 70 percent / tetrahydrofuran / 1 h / 20 °C 10.1: 55 percent / LiBH4 / dioxane / 0.5 h / 20 °C 11.1: 60 percent / aq. HCl / 0.5 h / Heating 12.1: 64 percent / morpholine / toluene / 3 h / Heating 13.1: [(CH3)3Si]2NLi / tetrahydrofuran / 0.5 h / -78 °C 13.2: 53 percent / (2R,8aS)-(+)-(camphorylsulfonyl)oxaziridine / tetrahydrofuran / 3 h / -78 °C View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342937', constants.ctx, '0')">potassium hydroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a> <br />Hydrolysis;&nbsp;12&nbsp;h;&nbsp;&nbsp;Heating;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 84 percent / TsOH / benzene / 4 h / Heating<br />2: aq. KOH / ethanol / 12 h / Heating<br /> <br /> &nbsp;