potassium hydroxide in N,N-dimethyl-formamide T=60 - 65°C; 20 h;

1: 87.7 percent / 30percent H2O2, conc.HCl / acetic acid / 0.5 h / 85 °C 2: 80.5 percent / methanol / 0.17 h / Heating 3: 56.8 percent / Zn, 1) AcOH, 2) HCl / methanol / Heating; 1) 10 min, 2) 5 min 4: KOH / dimethylformamide / 20 h / 60 - 65 °C View Scheme

1: 12 g / 1 N NaOH / 1 h / Ambient temperature 2: 87 percent / PPA / 0.67 h / 140 - 150 °C 3: 87.7 percent / 30percent H2O2, conc.HCl / acetic acid / 0.5 h / 85 °C 4: 80.5 percent / methanol / 0.17 h / Heating 5: 56.8 percent / Zn, 1) AcOH, 2) HCl / methanol / Heating; 1) 10 min, 2) 5 min 6: KOH / dimethylformamide / 20 h / 60 - 65 °C View Scheme

1: 87 percent / PPA / 0.67 h / 140 - 150 °C 2: 87.7 percent / 30percent H2O2, conc.HCl / acetic acid / 0.5 h / 85 °C 3: 80.5 percent / methanol / 0.17 h / Heating 4: 56.8 percent / Zn, 1) AcOH, 2) HCl / methanol / Heating; 1) 10 min, 2) 5 min 5: KOH / dimethylformamide / 20 h / 60 - 65 °C View Scheme

1: 80 percent / 15 h / 180 - 185 °C 2: 12 g / 1 N NaOH / 1 h / Ambient temperature 3: 87 percent / PPA / 0.67 h / 140 - 150 °C 4: 87.7 percent / 30percent H2O2, conc.HCl / acetic acid / 0.5 h / 85 °C 5: 80.5 percent / methanol / 0.17 h / Heating 6: 56.8 percent / Zn, 1) AcOH, 2) HCl / methanol / Heating; 1) 10 min, 2) 5 min 7: KOH / dimethylformamide / 20 h / 60 - 65 °C View Scheme

1: 80.5 percent / methanol / 0.17 h / Heating 2: 56.8 percent / Zn, 1) AcOH, 2) HCl / methanol / Heating; 1) 10 min, 2) 5 min 3: KOH / dimethylformamide / 20 h / 60 - 65 °C View Scheme

1: 56.8 percent / Zn, 1) AcOH, 2) HCl / methanol / Heating; 1) 10 min, 2) 5 min 2: KOH / dimethylformamide / 20 h / 60 - 65 °C View Scheme