2-BOC-氨基甲基-苯硼酸频那醇酯合成路线 （共 3 条）
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in N,N-dimethyl-formamide
T=80°C; Inert atmosphere;
参考文献
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; HENDRICKSON, Thomas, Francis; HO, Koc-Kan; SAUNDERS, Michael, David; STEVENS, Brian, John; SWIERCZEK, Krzysztof; WRIGHT, Kevin, Bret
Patent: WO2013/62945 A1, 2013 ;
Location in patent: Page/Page column 132 ;
WO 2013/062945 A1
反应条件
1: triethylamine / dichloromethane / 20 °C
2: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide / 80 °C / |Inert atmosphere
View Scheme
参考文献
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; HENDRICKSON, Thomas, Francis; HO, Koc-Kan; SAUNDERS, Michael, David; STEVENS, Brian, John; SWIERCZEK, Krzysztof; WRIGHT, Kevin, Bret
Patent: WO2013/62945 A1, 2013 ;
WO 2013/062945 A1
反应条件
1: triethylamine / dichloromethane / 20 °C
2: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide / 80 °C / |Inert atmosphere
View Scheme
参考文献
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; HENDRICKSON, Thomas, Francis; HO, Koc-Kan; SAUNDERS, Michael, David; STEVENS, Brian, John; SWIERCZEK, Krzysztof; WRIGHT, Kevin, Bret
Patent: WO2013/62945 A1, 2013 ;
WO 2013/062945 A1
