5-氯-1,3-二氢-3-甲基-2H-吲哚-2-酮合成路线 (共 2 条)
反应条件
hydrogen; palladium on activated charcoal in ethanol; ethyl acetate
P=2068.6 - 2585.7 Torr; Ambient temperature;
参考文献
RajanBabu, T. V.; Chenard, Bertrand L.; Petti, Michael A.
Journal of Organic Chemistry, 1986 , vol. 51, # 10 p. 1704 - 1712
反应条件
1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; caesium carbonate / tetrahydrofuran; water / 16 h / |Reflux
2: tri-ruthenium(0)dodecacarbonyl / chlorobenzene; N,N-dimethyl acetamide / 20 - 120 °C / |Sealed tube
View Scheme
参考文献
Li, Bin; Park, Yoonsu; Chang, Sukbok
Journal of the American Chemical Society, 2014 , vol. 136, # 3 p. 1125 - 1131