1-(2-甲氧基苯基)-1-己炔-3-醇合成路线 （共 9 条）
反应条件
1: 65 percent / BBr3 / CH2Cl2 / 3 h / Ambient temperature 2: 38 percent / n-BuLi / tetrahydrofuran / 2 h / -70 °C View Scheme
参考文献
Topolski, Marek
Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5588 - 5594
反应条件
1: 65 percent / BBr3 / CH2Cl2 / 3 h / Ambient temperature 2: 35 percent / n-BuLi / tetrahydrofuran / 2 h / -70 °C View Scheme
参考文献
Topolski, Marek
Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5588 - 5594
反应条件
1: 99 percent / H2O / ethyl acetate / 36 h / 20 °C 2: 96 percent / aq. HCl / dioxane / 71 h / Heating View Scheme
参考文献
Huh, Dal Ho; Jeong, Ji Sang; Lee, Hee Bong; Ryu, Hoejin; Kim, Young Gyu
Tetrahedron, 2002 , vol. 58, # 50 p. 9925 - 9932
反应条件
caesium carbonate; dimethyl sulfoxide T=115°C; 12 h;
参考文献
Zhao, Ming; Kuang, Chunxiang; Yang, Qing; Cheng, Xuezhi
Tetrahedron Letters, 2011 , vol. 52, # 9 p. 992 - 994
反应条件
triphenylphosphine in dichloromethane
T=0°C; 0.5 h;
参考文献
Huh, Dal Ho; Jeong, Ji Sang; Lee, Hee Bong; Ryu, Hoejin; Kim, Young Gyu
Tetrahedron, 2002 , vol. 58, # 50 p. 9925 - 9932
反应条件
triphenylphosphine monolith functionalized with carbon tetrabromide in dichloromethane
T=0°C; P=5171.62 Torr; Flow reactor;
参考文献
Roper, Kimberley A.; Berry, Malcolm B.; Ley, Steven V.
Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 1781 - 1790
反应条件
n-butyllithium
1.) THF, hexane, a) -78 deg C, 1 h, b) RT, 1 h, 2.) 2 h; Yield given. Multistep reaction;
参考文献
Barton, Thomas J.; Groh, Brian L.
Journal of Organic Chemistry, 1985 , vol. 50, # 2 p. 158 - 166
反应条件
n-butyllithium
1.) THF, hexane, a) -78 deg C, 1 h, b) RT, 1 h, 2.) 1 h; Yield given. Multistep reaction;
参考文献
Barton, Thomas J.; Groh, Brian L.
Journal of Organic Chemistry, 1985 , vol. 50, # 2 p. 158 - 166
反应条件
tris(dibenzylideneacetone)dipalladium (0); N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide
T=80°C; Stille reaction; 10 h;
参考文献
Shen, Wang; Wang, Le
Journal of Organic Chemistry, 1999 , vol. 64, # 24 p. 8873 - 8879
