N-Boc-L-烯丙基甘氨酸合成路线 （共 49 条）
反应条件
1: Et3N; DMAP / CH2Cl2 / 2 h / 20 °C 2: KMnO4; KOH / 2-methyl-propan-2-ol; H2O View Scheme
参考文献
Organic letters, , vol. 3, # 6 p. 897 - 899
反应条件
trifluoroacetic acid
参考文献
Tetrahedron Letters, , vol. 37, # 21 p. 3761 - 3764
反应条件
1: 94 percent / TFA; Et3SiH / CH2Cl2 / 15 h 2: 97 percent / NaOH / H2O; dioxane / 18 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 70, # 10 p. 3838 - 3844
反应条件
1: 92 percent / NaHCO3 / CHCl3; H2O / 1 h / 25 °C 2: 85 percent / NaOH / H2O; methanol / 3 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 65, # 22 p. 7310 - 7322
反应条件
1: 80.5 percent / sodium / ethanol / 4 h / Heating 2: 83.3 percent / 1N NaOH / ethanol / 16 h / 20 °C 3: 89.8 percent / xylene / 2 h / Heating 4: 95.8 percent / 24 h / 37 °C / α-chymotrypsin, 1N NaOH, 0.1M phosphate buffer, pH 7.5-8 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 58, # 3 p. 683 - 689
反应条件
1: 83.3 percent / 1N NaOH / ethanol / 16 h / 20 °C 2: 89.8 percent / xylene / 2 h / Heating 3: 95.8 percent / 24 h / 37 °C / α-chymotrypsin, 1N NaOH, 0.1M phosphate buffer, pH 7.5-8 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 58, # 3 p. 683 - 689
反应条件
1: Zn; AcOH / 70 °C 2: dioxane / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 19 p. 3311 - 3314
反应条件
1: 96 percent / LiOH / H2O; dioxane 2: 19 percent / BF3*Et2O / acetone; cyclohexane / 12 h 3: 50 percent / CuBr*Me2S / tetrahydrofuran / 4 h / -40 °C 4: trifluoroacetic acid View Scheme
参考文献
Tetrahedron Letters, , vol. 37, # 21 p. 3761 - 3764
反应条件
1: 50 percent / CuBr*Me2S / tetrahydrofuran / 4 h / -40 °C 2: trifluoroacetic acid View Scheme
参考文献
Tetrahedron Letters, , vol. 37, # 21 p. 3761 - 3764
反应条件
triethylamine in 1,4-dioxane; water 4 h; Ambient temperature;
参考文献
Tetrahedron, , vol. 47, # 29 p. 5453 - 5462
