1-二苯甲基-3-羟基氮杂环丁烷盐酸盐合成路线 （共 13 条）
反应条件
sodium hydride in DMF (N,N-dimethyl-formamide) T=0 - 25°C; 15.1667 h;
参考文献
FUJISAWA PHARMACEUTICAL CO., LTD.
Patent: WO2005/40151 A1, 2005 ;
Location in patent: Page/Page column 55-56 ;
WO 2005/040151 A1
反应条件
sodium carbonate in dichloromethane; water T=20°C;
参考文献
US2009/233903 A1, ;
Page/Page column 62 ;
US 20090233903 A1
反应条件
hydrogen; palladium on activated charcoal in ethanol; water T=20°C; P=2625.21 Torr; 4 h;
参考文献
Isoda, Takeshi; Ushirogochi, Hideki; Satoh, Koichi; Takasaki, Tsuyoshi; Yamamura, Itsuki; Sato, Chisato; Mihira, Ado; Abe, Takao; Tamai, Satoshi; Yamamoto, Shigeki; Kumagai, Toshio; Nagao, Yoshimitsu
Journal of Antibiotics, 2006 , vol. 59, # 4 p. 241 - 247
