1: 3-piperidin-1-yl-acrylic acid methyl ester; trifluoroacetyl fluoride With potassium fluoride in toluene T=-30 - 20°C; 4 h; 2: methylhydrazine in toluene T=-50 - 20°C; 3 h;

1: 3-piperidin-1-yl-acrylic acid methyl ester; difluoroacetic acid fluoride With potassium fluoride in toluene T=-30 - 20°C; 4 h; 2: methylhydrazine in toluene T=-50 - 20°C; 3 h; Product distribution / selectivity;