PPA

暂无反应条件数据

<b>Multi-step reaction with 4 steps<br /> </b>1: 91 percent / LiAlH₄ / diethyl ether / 10 h / 0 &deg;C<br />2: Et₃N / CH₂Cl₂ / 1 h / 0 &deg;C<br />3: NaI / acetone / 12 h / Heating<br />4: 1.) NaH, (iPr)2NH, 2.) n-BuLi / 1.) THF, 0 deg C and reflux, 15 min, 2.) THF, HMPA, 0 deg C, 15 min and 35 deg C 30 min, 3.) THF, HMPA, 0 deg C and 3 h, 25 deg C<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 1.) NaH, (iPr)2NH, 2.) n-BuLi / 1.) THF, 0 deg C and reflux, 15 min, 2.) THF, HMPA, 0 deg C, 15 min and 35 deg C 30 min, 3.) THF, HMPA, 0 deg C and 3 h, 25 deg C<br />2: 91 percent / LiAlH₄ / diethyl ether / 10 h / 0 &deg;C<br />3: Et₃N / CH₂Cl₂ / 1 h / 0 &deg;C<br />4: NaI / acetone / 12 h / Heating<br />5: 1.) NaH, (iPr)2NH, 2.) n-BuLi / 1.) THF, 0 deg C and reflux, 15 min, 2.) THF, HMPA, 0 deg C, 15 min and 35 deg C 30 min, 3.) THF, HMPA, 0 deg C and 3 h, 25 deg C<br /> <br /> &nbsp;