4-氯-3,5-二甲基苯甲酸合成路线 （共 1 条）
反应条件
1: 5-bromo-2-chloro-1,3-dimethylbenzene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.166667 h; Inert atmosphere;
2: carbon dioxide in tetrahydrofuran; hexane
T=-78°C;
3: With hydrogenchloride; water in tetrahydrofuran; hexane
参考文献
Asahi Kasei Pharma Corporation
Patent: US2009/298894 A1, 2009 ;
Location in patent: Page/Page column 45 ;
US 20090298894 A1
