1: sodium iodide / acetone / |Reflux 2: potassium carbonate / acetonitrile 3: sodium tetrahydroborate / methanol / 2 h / 0 - 5 °C / |Inert atmosphere 4: lithium aluminium tetrahydride / diethyl ether / 1.5 h / 20 °C / |Inert atmosphere 5: thionyl chloride / chloroform / |Reflux View Scheme

1.1: sodium iodide / acetone / |Reflux 2.1: potassium carbonate / acetonitrile 3.1: sodium tetrahydroborate / methanol / 2 h / 0 - 5 °C / |Inert atmosphere 4.1: lithium aluminium tetrahydride / diethyl ether / 1.5 h / 20 °C / |Inert atmosphere 5.1: Amano Lipase PS / toluene / 24 h 5.2: 24 h / 20 °C 6.1: sodium hydroxide; water / methanol / 1 h / 0 - 20 °C View Scheme

sodium iodide in acetone Heating;