5-氯-7-甲氧基-噻吩并[3,2-b]吡啶合成路线 （共 7 条）
参考文献
Jarvest, Richard L.; Armstrong, Sula A.; Berge, John M.; Brown, Pamela; Elder, John S.; Brown, Murray J.; Copley, Royston C.B.; Forrest, Andrew K.; Hamprecht, Dieter W.; O'Hanlon, Peter J.; Mitchell, Darren J.; Rittenhouse, Stephen; Witty, David R.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 15 p. 3937 - 3941
参考文献
Barker, John M.; Huddleston, Patrick R.; Holmes, David; Keenan, Guy J.; Wright, Brian
Journal of Chemical Research, Miniprint, 1984 , # 3 p. 771 - 795
反应条件
1: 68 percent / methanol / 2 h / Heating
2: 50 percent / aq.NaOH / 2 h / Heating
3: 55 percent / 0.25 h / 190 °C
View Scheme
参考文献
Barker, John M.; Huddleston, Patrick R.; Holmes, David; Keenan, Guy J.; Wright, Brian
Journal of Chemical Research, Miniprint, 1984 , # 3 p. 771 - 795
反应条件
1: 22 percent / POCl3
2: 68 percent / methanol / 2 h / Heating
3: 50 percent / aq.NaOH / 2 h / Heating
4: 55 percent / 0.25 h / 190 °C
View Scheme
参考文献
Barker, John M.; Huddleston, Patrick R.; Holmes, David; Keenan, Guy J.; Wright, Brian
Journal of Chemical Research, Miniprint, 1984 , # 3 p. 771 - 795
反应条件
1: 42 percent / methanol
2: 22 percent / POCl3
3: 68 percent / methanol / 2 h / Heating
4: 50 percent / aq.NaOH / 2 h / Heating
5: 55 percent / 0.25 h / 190 °C
View Scheme
参考文献
Barker, John M.; Huddleston, Patrick R.; Holmes, David; Keenan, Guy J.; Wright, Brian
Journal of Chemical Research, Miniprint, 1984 , # 3 p. 771 - 795
反应条件
1: 50 percent / aq.NaOH / 2 h / Heating
2: 55 percent / 0.25 h / 190 °C
View Scheme
参考文献
Barker, John M.; Huddleston, Patrick R.; Holmes, David; Keenan, Guy J.; Wright, Brian
Journal of Chemical Research, Miniprint, 1984 , # 3 p. 771 - 795
参考文献
Barker, John M.; Huddleston, Patrick R.; Holmes, David; Keenan, Guy J.; Wright, Brian
Journal of Chemical Research, Miniprint, 1984 , # 3 p. 771 - 795
