(S)-4-苄基-2-恶唑烷酮合成路线 （共 66 条）
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C 1.2: 2 h / -78 °C 2.1: anhydrous magnesium perchlorate / dichloromethane / 20 °C 2.2: -40 °C / |Schlenk technique View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 43 p. 8583 - 8586
反应条件
1: (S)-(-)-4-benzyl-2-oxazolidinone With n-butyllithium; triphenylemethane in tetrahydrofuran; hexane T=-78°C; 1 h; 2: 3-methyl-butyryl chloride in tetrahydrofuran; hexane T=-78 - 20°C; 2.5 h; 3: With potassium carbonate in tetrahydrofuran; hexane; water
参考文献
Nam, Gyeok; Ko, Soo Y.
Helvetica Chimica Acta, 2012 , vol. 95, # 10 p. 1937 - 1945,9
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane T=20°C; Cooling with ice;
参考文献
Jiao, Zhi-Gang; Chang, Xiao-Wei; Ding, Wei; Liu, Guo-Jun; Song, Ke-Sheng; Zhu, Nian-Yong; Zhang, Dan-Wei; Yang, Dan
Chemistry - An Asian Journal, 2011 , vol. 6, # 7 p. 1791 - 1799
反应条件
n-butyllithium in tetrahydrofuran T=-78°C;
参考文献
Son, Jung Beom; Kim, Si Nae; Kim, Na Yeong; Hwang, Min-Ho; Lee, Wonsun; Lee, Duck Hyung
Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 3 p. 653 - 663
反应条件
n-butyllithium in tetrahydrofuran T=0°C;
参考文献
Hailes, Helen C.; Handa, Sandeep; Leadlay, Peter F.; Lennon, Ian C.; Ley, Steven V.; Staunton, James
Tetrahedron Letters, 1994 , vol. 35, # 2 p. 315 - 318
反应条件
1: (S)-(-)-4-benzyl-2-oxazolidinone With N(Et)4ClO4 in acetonitrile T=20°C; Electrochemical reaction; 2: acetic anhydride With N(Et)4ClO4 in acetonitrile T=20°C; 3 h; Further stages.;
参考文献
Feroci, Marta; Inesi, Achille; Palombi, Laura; Sotgiu, Giovanni
Journal of Organic Chemistry, 2002 , vol. 67, # 5 p. 1719 - 1721
参考文献
Abbott Laboratories
Patent: US6133275 A1, 2000 ;
反应条件
nitric acid in dichloromethane T=20°C; 2 h;
参考文献
Ahmed, Sabbir; Adat, Shaheen; Murrells, Annabel; Owen, Caroline P.; Amanuel, Yonas
Bioorganic Chemistry, 2002 , vol. 30, # 5 p. 315 - 331
参考文献
Ishizuka, Tadao; Kimura, Koreichi; Ishibuchi, Seigo; Kunieda, Takehisa
Chemistry Letters, 1992 , # 6 p. 991 - 994
反应条件
1: 99 percent / nBuLi / tetrahydrofuran / 0 °C 2: 74 percent / NaN(SiMe3)2, DMPU / tetrahydrofuran / -78 °C View Scheme
参考文献
Hailes, Helen C.; Handa, Sandeep; Leadlay, Peter F.; Lennon, Ian C.; Ley, Steven V.; Staunton, James
Tetrahedron Letters, 1994 , vol. 35, # 2 p. 315 - 318
