N-chloro-succinimide in N,N-dimethyl-formamide
T=20°C; 72 h;
参考文献
Bolgunas, Stephen; Clark, David A.; Hanna, Wayne S.; Mauvais, Patricia A.; Pember, Steve O.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 15 p. 4762 - 4766
1: 18.45 g / HNO3; AcOH; Ac2O / 18 h / 20 °C
2: 98 percent / Et3N; H2 / Pd(OH)2/C / ethanol / 8 h / 20 °C / 2585.74 Torr
View Scheme
参考文献
Bolgunas, Stephen; Clark, David A.; Hanna, Wayne S.; Mauvais, Patricia A.; Pember, Steve O.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 15 p. 4762 - 4766
1: 18.45 g / HNO3; AcOH; Ac2O / 18 h / 20 °C
2: 98 percent / Et3N; H2 / Pd(OH)2/C / ethanol / 8 h / 20 °C / 2585.74 Torr
3: 74 percent / i-amylnitrite; AcOH / 1.5 h
View Scheme
参考文献
Bolgunas, Stephen; Clark, David A.; Hanna, Wayne S.; Mauvais, Patricia A.; Pember, Steve O.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 15 p. 4762 - 4766
