6,6-二甲基-3-(三氟甲基)-6,7-二氢-1H-吲唑-4(5H)-酮合成路线 （共 3 条）
反应条件
triethylamine in tetrahydrofuran T=55°C; 3 h;
参考文献
Taldone, Tony; Zatorska, Danuta; Patel, Pallav D.; Zong, Hongliang; Rodina, Anna; Ahn, James H.; Moulick, Kamalika; Guzman, Monica L.; Chiosis, Gabriela
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 8 p. 2603 - 2614
反应条件
1: toluene-4-sulfonic acid / toluene / 1.5 h / Reflux 2: triethylamine / tetrahydrofuran / 3 h / 55 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 19, # 8 p. 2603 - 2614
反应条件
1: trifluoroacetic anhydride; triethylamine / tetrahydrofuran / 2.75 h / 35 °C 2: sodium hydroxide; methanol / |Large scale View Scheme
参考文献
Organic Process Research and Development, , vol. 16, # 11 p. 1787 - 1793
