2-(2-二甲基氨基乙氧基)吡啶-4-胺合成路线 （共 3 条）
反应条件
sulfuric acid; copper(II) sulfate; sodium bromide; sodium nitrite in water T=0 - 20°C; 3 h;
参考文献
NOVARTIS AG
Patent: WO2009/118292 A1, 2009 ;
Location in patent: Page/Page column 86 ;
反应条件
hydrogenchloride; hydrogen; palladium 10 on activated carbon
T=20°C; P=3102.97 Torr; 3 h;
参考文献
SERENEX, INC.
Patent: WO2006/91963 A1, 2006 ;
Location in patent: Page/Page column 114-115 ;
反应条件
1: 2-(dimethylamino)-ethanol With sodium hydride in toluene
T=20°C; 0.666667 h;
2: 4-Amino-2-chloropyridine in toluene
16 h; Heating / reflux;
参考文献
CHUGAI SEIYAKU KABUSHIKI KAISHA
Patent: EP2050749 A1, 2009 ;
Location in patent: Page/Page column 138 ;
