in methanol T=20°C; 16 h;

1.1: lithium diisopropylamide / tetrahydrofuran / 0.03 h / -95 °C 1.2: 68 percent / iodine / tetrahydrofuran / -95 °C 2.1: 92 percent / methanol / 16 h / 20 °C View Scheme