(6CI,9CI)-1-(溴乙酰基)-吡咯烷合成路线 （共 6 条）
反应条件
1: 85 percent / benzene / 6 h / Heating 2: 98 percent / K2CO3 / acetonitrile / 4 h / 25 °C View Scheme
参考文献
Huang, Y. Z.; Shi, Lilan; Yang, Jianhua; Zhang, Jingtao
Tetrahedron Letters, 1987 , vol. 28, # 19 p. 2159 - 2162
反应条件
in dichloromethane
T=0 - 20°C; 1.5 h; Inert atmosphere;
参考文献
Kong, Han Il; Crichton, Jennifer E.; Manthorpe, Jeffrey M.
Tetrahedron Letters, 2011 , vol. 52, # 29 p. 3714 - 3717
反应条件
triethylamine in dichloromethane
T=0 - 20°C; 19 h;
参考文献
Bristol-Myers Squibb Company
Patent: US6344450 B1, 2002 ;
Location in patent: Page column 44 ;
US 6344450 B1
反应条件
in dichloromethane
T=-25 - 20°C; 3.5 h;
参考文献
Nechepurenko; Komarova; Vasil'ev; Salakhutdinov
Chemistry of Natural Compounds, 2013 , vol. 48, # 6 p. 1047 - 1053
Khim. Prir. Soedin., 2012 , vol. 48, # 6 p. 924 - 929,6
参考文献
Ishihara, Hiroyuki; Hori, Kiyoto; Sugihara, Hiroyasu; Ito, Yoshio N.; Katsuki, Tsutomu
Helvetica Chimica Acta, 2002 , vol. 85, # 12 p. 4272 - 4286
反应条件
1: 85 percent / benzene / 6 h / Heating
2: 82 percent / K2CO3 / acetonitrile / 7 h / 25 °C
View Scheme
参考文献
Huang, Y. Z.; Shi, Lilan; Yang, Jianhua; Zhang, Jingtao
Tetrahedron Letters, 1987 , vol. 28, # 19 p. 2159 - 2162
