2-氯-3-碘-4-吡啶胺合成路线

参考文献

Almirall, S.A.; Vidal Juan, Bernat; Alonso Diez, Juan Antonio; Buil Albero, María Antonia; Eastwood, Paul Robert; Esteve Trias, Cristina; Lozoya Toribio, María Estrella; Roberts, Richard Spurring; Vidal Gispert, Laura
Patent: EP2548876 A1, 2013 ;
Location in patent: Paragraph 0368; 0369 ;
EP 2548876 A1

14432-12-32-氯-4-氨基吡啶

800402-12-42-氯-5-碘-4-吡啶胺+

909036-46-02-氯-3-碘-4-吡啶胺

参考文献

WO2012/123745 A1, ;

Page/Page column 67-68 ;
WO 2012/123745 A1

14432-12-32-氯-4-氨基吡啶

800402-12-42-氯-5-碘-4-吡啶胺+

909036-46-02-氯-3-碘-4-吡啶胺+

1171919-00-8

参考文献

Jose, Gilish; Suresha Kumara; Nagendrappa, Gopalpur; Sowmya; Jasinski, Jerry P.; Millikan, Sean P.; Chandrika; More, Sunil S.; Harish
European Journal of Medicinal Chemistry, 2014 , vol. 77, p. 288 - 297

909036-46-02-氯-3-碘-4-吡啶胺+

34619-03-9

234108-74-8(2-氯-3-碘-4-吡啶)氨基甲酸1,1-二甲基乙酯

参考文献

ALMIRALL, S.A.; VIDAL JUAN, Bernat; ALONSO DIEZ, Juan Antonio; BUIL ALBERO, Maria Antonia; EASTWOOD, Paul Robert; ESTEVE TRIAS, Cristina; LOZOYA TORIBIO, Maria Estrella; ROBERTS, Richard Spurring; VIDAL GISPERT, Laura; GONZALEZ RODRIGUEZ, Jacob; MIR CEPEDA, Marta
Patent: WO2013/10880 A1, 2013 ;
Location in patent: Page/Page column 94-95 ;

909036-46-02-氯-3-碘-4-吡啶胺+

24424-99-5二碳酸二叔丁酯

234108-74-8(2-氯-3-碘-4-吡啶)氨基甲酸1,1-二甲基乙酯

参考文献

Almirall, S.A.; Vidal Juan, Bernat; Alonso Diez, Juan Antonio; Buil Albero, María Antonia; Eastwood, Paul Robert; Esteve Trias, Cristina; Lozoya Toribio, María Estrella; Roberts, Richard Spurring; Vidal Gispert, Laura
Patent: EP2548876 A1, 2013 ;
Location in patent: Paragraph 0370-0373 ;
EP 2548876 A1

909036-46-02-氯-3-碘-4-吡啶胺

854018-87-44-氯-2-甲基-1H-吡咯并[3,2-c]吡啶

参考文献

ALMIRALL, S.A.; VIDAL JUAN, Bernat; ALONSO DIEZ, Juan Antonio; BUIL ALBERO, Maria Antonia; EASTWOOD, Paul Robert; ESTEVE TRIAS, Cristina; LOZOYA TORIBIO, Maria Estrella; ROBERTS, Richard Spurring; VIDAL GISPERT, Laura; GONZALEZ RODRIGUEZ, Jacob; MIR CEPEDA, Marta
Patent: WO2013/10880 A1, 2013 ;