(3-苯基-5-异恶唑基)甲醇合成路线 （共 22 条）
反应条件
sodium chloride; triethylamine in tetrahydrofuran; water
反应条件
silver tetrafluoroborate; phenol in tetrahydrofuran 1 h; Reflux;
参考文献
Tetrahedron, , vol. 67, # 25 p. 4612 - 4615
反应条件
potassium hydrogencarbonate; copper(II) sulfate; sodium L-ascorbate in water; tert-butyl alcohol T=20°C; 1.5 h;
参考文献
Journal of the Chinese Chemical Society, , vol. 54, # 3 p. 643 - 652
反应条件
tert-butylhypochlorite in dichloromethane 5 h; Ambient temperature;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 4 p. 413 - 418
反应条件
1: Benzaldoxime With N-chloro-succinimide in N,N-dimethyl-formamide 3 h; 2: propargyl alcohol With CuSO4‵5H2O; potassium carbonate; ascorbic acid powder in N,N-dimethyl-formamide 1 h;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 50, # 5 p. 695 - 703
反应条件
n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.166667 h;
参考文献
Journal of Organic Chemistry, , vol. 56, # 13 p. 4252 - 4259
反应条件
1: N-chlorosuccinimide / dimethylformamide / Ambient temperature 2: Et3N / CH2Cl2 / 0 - 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 23 p. 4556 - 4566
反应条件
1: 80 percent / CCl4 / 1.) 0 degC, 2 h 2.) rt, 1 h 2: 1.6 M n-butyllithium / tetrahydrofuran; hexane / 0.17 h / -78 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 13 p. 4252 - 4259
反应条件
1.1: hydroxylamine hydrochloride; sodium carbonate / methanol; water / 4 h / 20 °C 2.1: N-chloro-succinimide / N,N-dimethyl-formamide / 3 h 2.2: 1 h View Scheme
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 50, # 5 p. 695 - 703
反应条件
1: toluene-4-sulfonic acid / dichloromethane / 0.25 h / 20 °C / |Inert atmosphere 2: tetrabutyl ammonium fluoride / tetrahydrofuran; dichloromethane / 0.5 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
European Journal of Organic Chemistry, , # 29 p. 5767 - 5773
