(8-甲基-8-氮杂双环[3.2.1]-3-辛基)甲醇合成路线 （共 4 条）
反应条件
hydrogen; bis(bicyclo[2.2.1]hepta-2,5-diene)dichlorodirhodium; tributylphosphine in benzene
T=100°C; P=60004.8 Torr; 6 h;
参考文献
Prokai-Tatrai, K.; Toeroes, S.; Heil, B.
Journal of Organometallic Chemistry, 1986 , vol. 315, p. 231 - 236
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=-78 - 20°C;
参考文献
Zhang, Suhong; Izenwasser, Sari; Wade, Dean; Xu, Liang; Trudell, Mark L.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 23 p. 7943 - 7952
参考文献
SmithKline Beecham p.l.c.
Patent: US6281226 B1, 2001 ;
反应条件
hydrogen; RhH(CO)(triphenylphosphine)3 in benzene
T=100°C; P=60004.8 Torr; 6 h; various catalysts, formed in situ from various phosphines; Product distribution;
参考文献
Prokai-Tatrai, K.; Toeroes, S.; Heil, B.
Journal of Organometallic Chemistry, 1986 , vol. 315, p. 231 - 236
