1: 100 percent / SmI2 / tetrahydrofuran; methanol / 0.08 h / -78 °C 2: 90 percent / hydrogen / Lindlar's catalyst / methanol / 3 h / 20 °C 3: KOH / ethane-1,2-diol / 12 h / 80 °C 4: 35.0 mg / potassium carbonate / acetone / 5 h / Heating View Scheme

<b>Multi-step reaction with 4 steps<br /> </b>1: 81 percent / triethylamine; p-toluenesulfonyl azide / acetonitrile / 6 h / 20 &deg;C<br />2: CuOTf; 3,3-di[(4S)-4-isopropyl-4,5-dihydro-1,3-oxazol-2-yl]pentane / toluene; benzene / 5 h / 50 &deg;C<br />3: 95 percent / dimethylsulfoxide / 5 h / 80 &deg;C<br />4: 59 percent / potassium carbonate; sodium iodide / dimethylformamide / 5 h / 20 &deg;C<br /> <br /> &nbsp;