(1-重氮-2-氧代-丙醇)-膦酸二甲酯合成路线

参考文献

Kallander, Lara S.; Lu, Qing; Chen, Wenfang; Tomaszek, Thaddeus; Yang, Guang; Tew, David; Meek, Thomas D.; Hofmann, Glenn A.; Schulz-Pritchard, Christina K.; Smith, Ward W.; Janson, Cheryl A.; Ryan, M. Dominic; Zhang, Gui-Feng; Johanson, Kyung O.; Kirkpatrick, Robert B.; Ho, Thau F.; Fisher, Paul W.; Mattern, Michael R.; Johnson, Randall K.; Hansbury, Michael J.; Winkler, James D.; Ward, Keith W.; Veber, Daniel F.; Thompson, Scott K.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5644 - 5647

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯+

1122-91-44-溴苯甲醛

766-96-1(4-溴苯基)乙炔

参考文献

Kallander, Lara S.; Lu, Qing; Chen, Wenfang; Tomaszek, Thaddeus; Yang, Guang; Tew, David; Meek, Thomas D.; Hofmann, Glenn A.; Schulz-Pritchard, Christina K.; Smith, Ward W.; Janson, Cheryl A.; Ryan, M. Dominic; Zhang, Gui-Feng; Johanson, Kyung O.; Kirkpatrick, Robert B.; Ho, Thau F.; Fisher, Paul W.; Mattern, Michael R.; Johnson, Randall K.; Hansbury, Michael J.; Winkler, James D.; Ward, Keith W.; Veber, Daniel F.; Thompson, Scott K.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5644 - 5647

104-87-0对甲基苯甲醛+

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯

766-97-24-甲苯基乙炔

参考文献

Synlett, , # 19 art. no. S07111ST, p. 2799 - 2802

66-77-31-萘甲醛+

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯

15727-65-8

参考文献

MacHin, Ben P.; Pagenkopf, Brian L.
Synlett, 2011 , # 19 art. no. S07111ST, p. 2799 - 2802

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯+

128376-64-7

1034287-04-1

参考文献

Synlett, , # 19 p. 3037 - 3041

1194059-56-7+

1194059-55-6+

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯

1194059-57-8+

1068-55-9

参考文献

ACHAOGEN, INC.
Patent: WO2009/137130 A2, 2009 ;
Location in patent: Page/Page column 267-268 ;

122-85-0+

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯

35447-83-7

参考文献

Vernekar, Sanjeev Kumar V.; Qiu, Li; Zacharias, Jeana; Geraghty, Robert J.; Wang, Zhengqiang
MedChemComm, 2014 , vol. 5, # 5 p. 603 - 608

316141-37-4

参考文献

IDENIX PHARMACEUTICALS, INC.
Patent: WO2009/14730 A1, 2009 ;
Location in patent: Page/Page column 114-115 ;
WO 2009/014730 A1

59378-82-4+

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯

316141-37-4

参考文献

Alcaide, Benito; Almendros, Pedro; Quiros, M. Teresa; Fernandez, Israel
Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 818 - 826

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯+

115186-37-3

130418-90-5

参考文献

Ying, Weijiang; Herndon, James W.
European Journal of Organic Chemistry, 2013 , # 15 p. 3112 - 3122