1,2-二(溴甲基)苯合成路线 （共 196 条）
反应条件
1: sodium hydroxide; toluene / 200 °C
2: acetic acid / 80 - 90 °C / Beim Leiten eines Gemisches von Stickstoffdioxid und Sauerstoff in eine Loesung
View Scheme
参考文献
Wegler; Frank
Chemische Berichte, 1937 , vol. 70, p. 1279,1285
反应条件
1: sodium; THF; tetraphenylethene / -80 °C
2: CCl4; N-bromo-succinimide
3: quinoline / 125 - 130 °C
View Scheme
参考文献
Cope; Fenton
Journal of the American Chemical Society, 1951 , vol. 73, p. 1668,1672
反应条件
1: sodium; THF; tetraphenylethene / -80 °C
2: CCl4; N-bromo-succinimide
3: acetic acid
4: ethanolic NaOH
5: chromium (VI)-oxide; acetic acid
View Scheme
参考文献
Cope; Fenton
Journal of the American Chemical Society, 1951 , vol. 73, p. 1668,1672
反应条件
TMS-SnBu3; cesium fluoride in N,N-dimethyl-formamide
4 h; Ambient temperature;
参考文献
Sato, Hiroki; Isono, Naohiro; Miyoshi, Irie; Mori, Miwako
Tetrahedron, 1996 , vol. 52, # 24 p. 8143 - 8158
反应条件
1: 90.9 percent / K2CO3 / dimethylformamide / 4 h / 60 °C
2: 93.5 percent / MeONa / toluene; tetrahydrofuran; 1,2-dimethoxy-ethane / 0.5 h / 0 °C
3: 70 percent / aq. NaOH / tetrahydrofuran; methanol / 20 °C
View Scheme
参考文献
Long, Ya-Qiu; Jiang, Xiao-Hua; Dayam, Raveendra; Sanchez, Tino; Shoemaker, Robert; Sei, Shizuko; Neamati, Nouri
Journal of Medicinal Chemistry, 2004 , vol. 47, # 10 p. 2561 - 2573
反应条件
1: 66.1 percent / sodium sulfide nonahydrate; benzyltriethylammonium chloride / benzene; H2O / 30 h / 20 °C
2: 89.5 percent / acetic acid; H2O2 / 4 h / 20 - 95 °C
3: 81.2 percent / nitric acid; acetic acid; Ac2O / 5 h / 10 °C
4: 81.4 percent / tin; hydrochloric acid / ethanol / 8 h / Heating
View Scheme
参考文献
Tashbaev
Russian Chemical Bulletin, 2005 , vol. 54, # 2 p. 437 - 440
反应条件
1: 89 percent / Na2S, triethylhexadecylammonium chloride / CH2Cl2; H2O / 18 h / Ambient temperature; dark
2: H2O2 / acetic acid
3: 1.) BuLi / 1.) Et2O, -78 deg C -> room temperature; room temperature, 1 h, 2.) -78 deg C -> room temperature; room temperature, 2 h
4: 550 °C / 0.01 Torr
View Scheme
参考文献
Durst, Tony; Lancaster, Michael; Smith, David J. H.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1846 - 1848
反应条件
diiron nonacarbonyl in benzene
参考文献
Holland,J.M.; Jones,D.W.
Journal of the Chemical Society [Section] C: Organic, 1970 , p. 530 - 536
反应条件
potassium hydroxide in ethanol
12 h; Ambient temperature;
参考文献
Lai, Yee-Hing
Journal of Organic Chemistry, 1988 , vol. 53, # 10 p. 2360 - 2362
反应条件
S(MgBr)2 in tetrahydrofuran
4 h; Heating;
参考文献
Nedugov, A. N.; Pavlova, N. N.
Journal of Organic Chemistry USSR (English Translation), 1992 , vol. 28, # 7.1 p. 1103 - 1104
Zhurnal Organicheskoi Khimii, 1992 , vol. 28, # 7 p. 1401 - 1402
