1,2-二(溴甲基)苯合成路线 （共 196 条）
反应条件
1: 75 percent / NaOMe / 4 h / Heating 2: 1.) KOH, 2.) 2 N HCl / 1.) MeOH, H2O, reflux, 4 h, 2.) EtOAc, pH 1 View Scheme
参考文献
Kammermeier; Lerch; Sommer
Synthesis, 1992 , # 11 p. 1157 - 1160
反应条件
1: ethanol / 3 h / Heating 2: aq. KOH / ethanol / 1 h / Heating 3: LiAlH4 / diethyl ether View Scheme
参考文献
Pifferi,G. et al.
Gazzetta Chimica Italiana, 1966 , vol. 96, p. 1671 - 1695
反应条件
Boc2NH; sodium hydride in N,N-dimethyl-formamide
参考文献
Journal of Organic Chemistry, , vol. 29, p. 2820 - 2824
反应条件
anschliesendes Erwaermen mit wss.NaOH;
参考文献
Trudy Kazansk.chim.technol.Inst.Chem.Abstr., , # 23 p. 197,199
Trudy Kazansk.chim.technol.Inst.Chem.Abstr., , p. 8988
反应条件
in tert-butyl alcohol
反应条件
water; N-ethyl-N,N-diisopropylamine; triphenylphosphine; Na2[PdCl4] in various solvent(s) T=70°C; P=760 Torr;
参考文献
Journal of Organometallic Chemistry, , vol. 691, # 11 p. 2378 - 2385
反应条件
2: NBS 3: (i) collidine, DMSO, (ii) H2O View Scheme
参考文献
Yates,P. et al.
Canadian Journal of Chemistry, 1970 , vol. 48, p. 788 - 795
反应条件
lithium 1 h; Irradiation;
参考文献
Boudjouk, Philip; Sooriyakumaran, Ratnasabapathy; Han, Byung-Hee
Journal of Organic Chemistry, 1986 , vol. 51, # 14 p. 2818 - 2819
反应条件
chromium dichloride in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide
参考文献
Stephan, D.; Gorgues, A.; le Coq, A.
Tetrahedron Letters, 1984 , vol. 25, # 49 p. 5649 - 5652
反应条件
sodium hydride in N,N-dimethyl-formamide T=20°C; 1 h;
参考文献
Otani, Yuko; Nagae, Osamu; Naruse, Yuji; Inagaki, Satoshi; Ohno, Masashi; Yamaguchi, Kentaro; Yamamoto, Gaku; Uchiyama, Masanobu; Ohwada, Tomohiko
Journal of the American Chemical Society, 2003 , vol. 125, # 49 p. 15191 - 15199
