1,2-二(溴甲基)苯合成路线 （共 196 条）
反应条件
sodium hydroxide in 1,4-dioxane T=20°C; 0.5 h;
参考文献
Subbarayappa, Adimurthy; Patoliya, Paresh U.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2009 , vol. 48, # 4 p. 545 - 552
反应条件
1: Cyclization; 2: With potassium hydroxide Hydrolysis; Further stages.;
参考文献
Miller, Glen P.; Mack, James
Organic Letters, 2000 , vol. 2, # 25 p. 3979 - 3982
反应条件
1: aqueous hydrobromic acid; chloroform / Behandeln einer heissen Loesung des Reaktionsprodukts in wss. Ammoniak mit Kaliumjodid 2: potassium amide; liquid ammonia View Scheme
参考文献
Wittig et al.
Justus Liebigs Annalen der Chemie, 1951 , vol. 572, p. 1,21
反应条件
2: NBS 3: (i) collidine, DMSO, (ii) H2O View Scheme
参考文献
Yates,P. et al.
Canadian Journal of Chemistry, 1970 , vol. 48, p. 788 - 795
反应条件
1: toluene-4-sulfonamide With sodium hydride in N,N-dimethyl-formamide; mineral oil T=65°C; 1 h; Inert atmosphere; 2: 1,2-bis-(bromomethyl)benzene in N,N-dimethyl-formamide; mineral oil T=65°C; 3 h; Inert atmosphere;
参考文献
Anastasiadis, Charalampos; Hogarth, Graeme; Wilton-Ely, James D.E.T.
Inorganica Chimica Acta, 2010 , vol. 363, # 13 p. 3222 - 3228
反应条件
in N,N-dimethyl-formamide T=80°C; 5 h;
参考文献
Bottino, Francesco; Grazia, Michele Di; Finocchiaro, Paolo; Fronczek, Frank R.; Mamo, Antonino; Pappalardo, Sebastiano
Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3521 - 3529
Title/Abstract Full Text View citing articles Show Details
Pappalardo, Sebastiano; Bottino, Francesco; Grazia, Michele Di; Finocchiaro, Paolo; Mamo, Antonino
Heterocycles, 1985 , vol. 23, # 8 p. 1881 - 1884
反应条件
1: methanol 2: zinc chloride; tetrachloromethane / Erhitzen des Reaktionsprodukts mit Kaliumcyanid in wss. Aethanol 3: ethanolic KOH-solution 4: phosphorus oxychloride / Erwaermen des Reaktionsprodukts mit wss. Kalilauge View Scheme
参考文献
Murahashi
Scientific Papers of the Institute of Physical and Chemical Research (Japan), 1936 , vol. 30, p. 180,188
反应条件
sodium hydroxide; potassium carbonate in water T=120°C; P=2068.59 - 4137.18 Torr; 0.333333 h; microwave irradiation;
参考文献
Ju, Yuhong; Varma, Rajender S.
Tetrahedron Letters, 2005 , vol. 46, # 36 p. 6011 - 6014
反应条件
ethanol; methylamine Erwaermen des Reaktionsprodukts mit wss. Natronlauge;
参考文献
Wittig et al.
Justus Liebigs Annalen der Chemie, 1951 , vol. 572, p. 1,21
反应条件
1: K2CO3 / acetonitrile / 6 h / Heating 2: 85 percent / KOH / H2O; methanol / 3 h / Heating View Scheme
参考文献
Munoz, Cynthia R. Trejo; Percino, Teresa Mancilla; Jimenez, Elvia Mera; Correa-Basurto, Jose; Ferrara, Jose G. Trujillo
Medicinal Chemistry Research, 2013 , vol. 22, # 8 p. 4039 - 4045
