反应条件
1: 69 percent / AlCl3 / nitrobenzene / 12 h / Ambient temperature
2: 94 percent / Et3SiH, CF3CO2H / 6 h
3: 74.5 percent / polyphosphoric acid (PPA) / 1.25 h / 75 °C
4: 96 percent / LAH / tetrahydrofuran / 3 h / Ambient temperature
5: 98.5 percent / MgSO4 / benzene / 1 h / Heating
6: NaHCO3 / benzene / 0.17 h / Ambient temperature
7: 88.6 percent / 1.) BBr3 / CH2Cl2 / 1.) RT, 10 h, 2.) RT, 5 h
View Scheme
参考文献
Hamada, Akihiko; Chang, Yu An; Uretsky, Norman; Miller, Duane D.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 675 - 680
