1,2,3,4-四氢异喹啉合成路线 （共 340 条）
参考文献
v. Braun; Goll
Chemische Berichte, 1927 , vol. 60, p. 341
反应条件
in N,N-dimethyl-formamide; acetone T=0 - 20°C; Inert atmosphere;
参考文献
Jamieson, Stephen M. F.; Brooke, Darby G.; Heinrich, Daniel; Atwell, Graham J.; Silva, Shevan; Hamilton, Emma J.; Turnbull, Andrew P.; Rigoreau, Laurent J. M.; Trivier, Elisabeth; Soudy, Christelle; Samlal, Sharon S.; Owen, Paul J.; Schroeder, Ewald; Raynham, Tony; Flanagan, Jack U.; Denny, William A.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 17 p. 7746 - 7758
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene; bis(η3-allyl-μ-chloropalladium(II)); triethyl phosphite in tetrahydrofuran T=20°C; 20 h; Title compound not separated from byproducts.;
参考文献
Dubovyk, Igor; Watson, Iain D. G.; Yudin, Andrei K.
Journal of Organic Chemistry, 2013 , vol. 78, # 4 p. 1559 - 1575
反应条件
bis(η3-allyl-μ-chloropalladium(II)); 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in tetrahydrofuran T=20°C;
参考文献
Dubovyk, Igor; Watson, Iain D. G.; Yudin, Andrei K.
Journal of Organic Chemistry, 2013 , vol. 78, # 4 p. 1559 - 1575
反应条件
C21H38AuClNP*C24BF20(1-)*K(1+) in benzene-d6 T=90°C; Markovnikov hydroamination; 12 h; Inert atmosphere;
参考文献
Xiaoming, Zeng; Soleilhavoup, Michele; Bertrand, Guy
Organic Letters, 2009 , vol. 11, # 15 p. 3166 - 3169
反应条件
sodium hydroxide in water T=90°C; 24 h;
参考文献
Preedasuriyachai, Patcharee; Chavasiri, Warinthorn; Sakurai, Hidehiro
Synlett, 2011 , # 8 art. no. U00511ST, p. 1121 - 1124
反应条件
sodium hydroxide in water; tert-butyl alcohol 24 h; Reflux;
参考文献
Synlett, , # 8 art. no. U00511ST, p. 1121 - 1124
反应条件
sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene in tetrahydrofuran; water T=20°C; Pinnick oxidation; 20 h;
参考文献
Tetrahedron Letters, , vol. 50, # 26 p. 3436 - 3438
反应条件
1-tert-butylperoxy-1,2-benziodoxol-3(1H)-one in benzene 120 h; Ambient temperature;
参考文献
Heterocycles, , vol. 46, # 1 p. 71 - 76
反应条件
1: concentrated sulfuric acid; potassium nitrate 2: mercury (II)-acetate; aqueous acetic acid / 150 °C View Scheme
参考文献
Shi, Jun; Manolikakes, Georg; Yeh, Chien-Hung; Guerrero, Carlos A.; Shenvi, Ryan A.; Shigehisa, Hiroki; Baran, Phil S.
Journal of the American Chemical Society, 2011 , vol. 133, # 20 p. 8014 - 8027
