1,2,3,4-四氢异喹啉合成路线 （共 340 条）
反应条件
triethylamine in dichloromethane
1 h; Yield givenYields of byproduct given;
参考文献
Yokoyama, Akihiro; Ohwada, Tomohiko; Shudo, Koichi
Journal of Organic Chemistry, 1999 , vol. 64, # 2 p. 611 - 617
反应条件
1: 95 percent / 16 h / 25 °C
2: 66 percent / AlCl3 / CS2 / 1 h / Heating
3: 83 percent / 3N aq. HCl / butan-1-ol / 3 h / Heating
View Scheme
参考文献
Ali; Gleason; Hill; Krell; Kruse; Lavanchy; Volpe
Journal of Medicinal Chemistry, 1982 , vol. 25, # 10 p. 1235 - 1240
参考文献
Coyle, John D.; Bryant, Laurence, R. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2857 - 2865
反应条件
1: in dichloromethane
T=60°C;
2: With isatoic anhydride-N-(CH2)3-C8F17 in dichloromethane
T=60°C; 2.5 h;
参考文献
Zhang, Wei; Chen, Christine Hiu-Tung; Nagashima, Tadamichi
Tetrahedron Letters, 2003 , vol. 44, # 10 p. 2065 - 2068
反应条件
1: in acetonitrile
P=760.051 Torr; 0.166667 h; Inert atmosphere;
2: With tributylphosphine; di-tert-butylazodicarboxylate in acetonitrile
Mitsunobu reaction; P=760.051 Torr; Inert atmosphere;
参考文献
Peterson, Scott L.; Stucka, Sabrina M.; Dinsmore, Christopher J.
Organic Letters, 2010 , vol. 12, # 6 p. 1340 - 1343
反应条件
1: 88 percent / pyridine / CH2Cl2 / 2 h / 20 °C
2: 71 percent / triethylamine / CH2Cl2 / 12 h / 20 °C
View Scheme
参考文献
Lemoucheux, Laurent; Rouden, Jacques; Ibazizene, Meziane; Sobrio, Franck; Lasne, Marie-Claire
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7289 - 7297
参考文献
Chinoin Gyogyszer es Vesgyeszeti Termekek Gyara R. T.
Patent: US4435567 A1, 1984 ;
反应条件
18-crown-6 ether; potassium carbonate; potassium iodide in toluene
T=100°C; 14 h;
参考文献
Zablotskaya; Segal; Lukevics
Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 7 p. 958 - 959
反应条件
1: 48 percent / KOH; KI; Aliquat(R)-336 / benzene / Heating
View Scheme
参考文献
Segal; Zablotskaya; Lukevics
Chemistry of Heterocyclic Compounds, 2005 , vol. 41, # 5 p. 613 - 624
参考文献
Coyle, John D.; Bryant, Laurence R.B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 3 p. 531 - 534
