2,4-二甲氧基苯甲酸合成路线 （共 127 条）
反应条件
1: Et3N; diphenylphosphorazidate / benzene / 0.67 h 2: benzene / Heating View Scheme
参考文献
Maiti, Arup; Reddy, P. V. Narasimha; Sturdy, Megan; Marler, Laura; Pegan, Scott D.; Mesecar, Andrew D.; Pezzuto, John M.; Cushman, Mark
Journal of Medicinal Chemistry, 2009 , vol. 52, # 7 p. 1873 - 1884
反应条件
1: LiAlH4; SOCl2 2: aqueous NaOH View Scheme
参考文献
Shepard et al.
Journal of Organic Chemistry, 1952 , vol. 17, p. 568,570
反应条件
silver carbonate; copper dichloride; palladium dichloride in tetrahydrofuran T=110°C; 24 h;
参考文献
Peng, Xuefeng; Shao, Xiang-Feng; Liu, Zhong-Quan
Tetrahedron Letters, 2013 , vol. 54, # 24 p. 3079 - 3081
反应条件
sodium tetrahydroborate; sodium sulfate; dihydroxy(3,4,5-trifluorophenyl)borane in tetrahydrofuran T=20°C; 10 h;
参考文献
Tale; Patil; Dapurkar
Tetrahedron Letters, 2003 , vol. 44, # 16 p. 3427 - 3428
反应条件
1: 4-methoxy-2-methoxy benzoic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=20°C; 0.5 h; 2: methanol With sodium tetrahydroborate in tetrahydrofuran T=0°C; 0.5 h;
参考文献
Synthesis, , # 9 art. no. M12811SS, p. 1375 - 1382
反应条件
1: 4-methoxy-2-methoxy benzoic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=20°C; 0.5 h; 2: isopropyl alcohol With sodium tetrahydroborate in tetrahydrofuran T=0°C; 0.5 h;
参考文献
Synthesis, , # 9 art. no. M12811SS, p. 1375 - 1382
反应条件
triphenylphosphine; silver carbonate; palladium dichloride in dimethyl sulfoxide T=130°C; 6 h; Inert atmosphere;
参考文献
Xie, Kai; Wang, Sizhuo; Yang, Zhiyong; Liu, Jidan; Wang, Anwei; Li, Xiujian; Tan, Ze; Guo, Can-Cheng; Deng, Wei
European Journal of Organic Chemistry, 2011 , # 29 p. 5787 - 5790
反应条件
triphenylphosphine; silver carbonate; palladium dichloride in dimethyl sulfoxide T=130°C; 6 h; Inert atmosphere;
参考文献
Xie, Kai; Wang, Sizhuo; Yang, Zhiyong; Liu, Jidan; Wang, Anwei; Li, Xiujian; Tan, Ze; Guo, Can-Cheng; Deng, Wei
European Journal of Organic Chemistry, 2011 , # 29 p. 5787 - 5790
反应条件
silver carbonate in dimethyl sulfoxide T=140°C; 16 h;
参考文献
Chemical Communications, , # 46 p. 7176 - 7178
反应条件
silver carbonate; copper(ll) bromide; palladium dichloride in tetrahydrofuran T=110°C; 24 h; SolventReagent/catalystTime;
参考文献
Tetrahedron Letters, , vol. 54, # 24 p. 3079 - 3081
