1: indole-2,3-dione With sodium hydride in tetrahydrofuran; mineral oil T=0°C; 2 h; 2: 2-chlorophenylmethyl bromide in tetrahydrofuran; mineral oil T=20°C;
参考文献
WAYNE STATE UNIVERSITY; DEPARTMENT OF VETERANS AFFAIRS; REGENTS OF THE UNIVERSITY OF MICHIGAN; RISHI, Arun, K.; LARSEN, Scott, D.
Patent: WO2013/33392 A1, 2013 ;
Location in patent: Page/Page column 62-63 ;
1: indole-2,3-dione With sodium hydride in N,N-dimethyl-formamide; mineral oil T=0°C; 2 h; 2: methyl iodide in N,N-dimethyl-formamide; mineral oil T=20°C; 2 h;
参考文献
Bergonzini, Giulia; Melchiorre, Paolo
Angewandte Chemie - International Edition, 2012 , vol. 51, # 4 p. 971 - 974
1: With benzoic acid; hydrazine in tetrahydrofuran T=20°C; 16 h; 2: With N-iodo-N-potassio-p-toluenesulphonamide; potassium hydroxide in tetrahydrofuran; water T=20°C;
参考文献
Nicolle, Simon M.; Moody, Christopher J.
Chemistry - A European Journal, 2014 , vol. 20, # 15 p. 4420 - 4425
