1: acetonitrile 2: H2 / PtO2 3: NaIO4, RuO2 View Scheme

1: acetonitrile 2: H2 / PtO2 3: NaIO4, RuO2 View Scheme

1: (2-oxo-propyl)-phosphonic acid dimethyl ester With 4-Acetylaminobenzenesulfonyl Azide; potassium carbonate in acetonitrile 2 h; 2: N-tert.-butyloxycarbonyl-L-serinal in methanol; acetonitrile T=20°C; 3: With potassium carbonate in methanol; acetonitrile 24 h;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11343357', constants.ctx, '0')">sodium periodate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />T=4&deg;C;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 89 percent / imidazole / dimethylformamide / 120 h / 50 &deg;C<br />2: 25 g / DIBAL / toluene / 2 h / -70 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 90 percent / NaOCH₃ / methanol<br />2: NaBH₄ / ethanol / 24 h / 20 &deg;C<br />3: 80 percent / NaIO₄ / H₂O / 4 &deg;C<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1696847', constants.ctx, '0')">dimethylsulfide</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '4921393', constants.ctx, '0')">ozone</a> <br />&nbsp;1) MeOH, -78 deg C, 2) -78 deg C, 3 h to room temp., 1 h;&nbsp;&nbsp;Multistep reaction;&nbsp;<br /> &nbsp;