(S)-4-甲基苯磺酰基氧基-1,2-环氧丁烷合成路线 （共 3 条）
反应条件
1: (R)-2-bromo-1,4-butanediol With sodium hydride in tetrahydrofuran
T=-10°C; 0.5 h;
2: p-toluenesulfonyl chloride in tetrahydrofuran
T=-10°C; 4 h;
参考文献
Boeckman Jr., Robert K.; Clark, Tammy J.; Shook, Brian C.
Helvetica Chimica Acta, 2002 , vol. 85, # 12 p. 4532 - 4560
反应条件
1: pyridinium p-toluenesulfonate / methanol / 14 h / 21 °C
2: K2CO3 / methanol / 7 h
View Scheme
参考文献
Bartlett; Meadows; Ottow
Journal of the American Chemical Society, 1984 , vol. 106, # 18 p. 5304 - 5311
参考文献
Boeckman Jr., Robert K.; Clark, Tammy J.; Shook, Brian C.
Organic Letters, 2002 , vol. 4, # 12 p. 2109 - 2112
