2-[[[1-(4-乙基-3,4-二氢-3-氧代-2H-1,4-苯并噻嗪-6-基)亚乙基]氨基]氧基]-乙酸乙酯合成路线 （共 6 条）
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate
0.5 h; Ambient temperature;
参考文献
Shridhar, D. R.; Sastry, C. V. Reddy; Bansal, O. P.; Rao, Pulla; Singh, P. P.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 12 p. 1236 - 1242
反应条件
1: 60 percent / NaHCO3 / aq. ethanol / 2 h / Heating
2: 55 percent / FeSO4*7H2O / aq. NH3 / 1 h / Heating
3: 86 percent / KOH / acetone / 5 h / Heating
4: 70 percent / NH2OH*HCl, pyridine / ethanol / 2 h / Heating
5: 78 percent / aq.NaOH / tetrabutylammonium hydrogen sulphate / 0.5 h / Ambient temperature
View Scheme
参考文献
Shridhar, D. R.; Sastry, C. V. Reddy; Bansal, O. P.; Rao, Pulla; Singh, P. P.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 12 p. 1236 - 1242
反应条件
1: 86 percent / KOH / acetone / 5 h / Heating
2: 70 percent / NH2OH*HCl, pyridine / ethanol / 2 h / Heating
3: 78 percent / aq.NaOH / tetrabutylammonium hydrogen sulphate / 0.5 h / Ambient temperature
View Scheme
参考文献
Shridhar, D. R.; Sastry, C. V. Reddy; Bansal, O. P.; Rao, Pulla; Singh, P. P.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 12 p. 1236 - 1242
反应条件
1: 70 percent / NH2OH*HCl, pyridine / ethanol / 2 h / Heating
2: 78 percent / aq.NaOH / tetrabutylammonium hydrogen sulphate / 0.5 h / Ambient temperature
View Scheme
参考文献
Shridhar, D. R.; Sastry, C. V. Reddy; Bansal, O. P.; Rao, Pulla; Singh, P. P.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 12 p. 1236 - 1242
反应条件
1: 55 percent / FeSO4*7H2O / aq. NH3 / 1 h / Heating
2: 86 percent / KOH / acetone / 5 h / Heating
3: 70 percent / NH2OH*HCl, pyridine / ethanol / 2 h / Heating
4: 78 percent / aq.NaOH / tetrabutylammonium hydrogen sulphate / 0.5 h / Ambient temperature
View Scheme
参考文献
Shridhar, D. R.; Sastry, C. V. Reddy; Bansal, O. P.; Rao, Pulla; Singh, P. P.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 12 p. 1236 - 1242
反应条件
1: 85 percent / aq.NaOH / 2 h / Heating
2: 80 percent / Et3N / dimethylformamide / 2 h / Heating
View Scheme
参考文献
Shridhar, D. R.; Sastry, C. V. Reddy; Bansal, O. P.; Rao, Pulla; Singh, P. P.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 12 p. 1236 - 1242
