2-(4-乙酰基苯氧基)丙酸合成路线 (共 5 条)
反应条件
sodium hydroxide in water
参考文献
Hoechst Celanese Corporation
Patent: US4883901 A1, 1989 ;
反应条件
potassium hydroxide in ethanol; water
T=0°C; 4 h;
参考文献
Kato, Dai-Ichiro; Mitsuda, Satoshi; Ohta, Hiromichi
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7234 - 7242
反应条件
1: 42 percent / sodium hydride / tetrahydrofuran / 14 h / 20 °C
2: 100 percent / potassium hydroxide / ethanol; H2O / 4 h / 0 °C
View Scheme
参考文献
Kato, Dai-Ichiro; Mitsuda, Satoshi; Ohta, Hiromichi
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7234 - 7242
反应条件
1: 35.4 percent / conc. H2SO4 / 6 h / Heating
2: Br2, gl. acetic acid / 0.5 h / 0 °C
3: 60 percent / ethanol / Heating
4: 58 percent / 20percent aq. H2SO4 / Heating
View Scheme
参考文献
Singh, S. P.; Vaid, R. K.; Bathla, Kamla
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 119 - 123
反应条件
1: 35.4 percent / conc. H2SO4 / 6 h / Heating
2: Br2, gl. acetic acid / 0.5 h / 0 °C
3: 58 percent / ethanol / Heating
4: 49 percent / 20percent aq. H2SO4 / Heating
View Scheme
参考文献
Singh, S. P.; Vaid, R. K.; Bathla, Kamla
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 119 - 123