1: 87 percent / wet Al2O3; Oxone / CH2Cl2 / 3 h / Heating 2: 86 percent / dppe; KOH / [Pd(C3H5)Cl]2 / CH2Cl2; H2O / 1 h / 20 °C View Scheme

1: dihydrogen peroxide / 2,2,2-trifluoroethanol; water / 0 - 20 °C 2: (1S,2S,4S,5R)-1-(anthracen-9-ylmethyl)-2-((R)-hydroxy(quinolin-4-yl)methyl)-5-vinyl-1-azoniabicyclo[2.2.2]octane chloride; sodium hydroxide / water; toluene / 36 h / -20 °C / Inert atmosphere View Scheme

dihydrogen peroxide in 2,2,2-trifluoroethanol; water T=0 - 20°C;