3-(乙基氨基甲基)吡咯烷合成路线 （共 5 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile
1.) reflux, 3 h, 2.) room temperature, 18 h;
参考文献
Sanchez, Joseph P.; Domagala, John M.; Hagen, Susan E.; Heifetz, Carl L.; Hutt, Marland P.; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, p. 983 - 991
反应条件
trimethylsilyl iodide in dichloromethane; acetonitrile
参考文献
Warner-Lambert Company
Patent: US4578473 A1, 1986 ;
参考文献
Warner-Lambert Company
Patent: US4771054 A1, 1988 ;
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile
1.) reflux, 2.5 h, 2.) room temperature, overnight;
参考文献
Domagala, John M.; Heifetz, Carl L.; Hutt, Marland P.; Mich, Thomas F.; Nichols, Jeffry B.; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 5 p. 991 - 1001
参考文献
Warner-Lambert Company
Patent: US4771054 A1, 1988 ;
