2-甲基-2-丙基2-环己烯-1-基氨基甲酸酯合成路线 （共 9 条）
反应条件
sodium naphthalenide in ethylene glycol dimethyl ether
Ambient temperature;
参考文献
Henry, James R.; Marcin, Lawrence R.; McIntosh, Matthias C.; Scola, Paul M.; Harris, G. Davis; Weinreb, Steven M.
Tetrahedron Letters, 1989 , vol. 30, # 42 p. 5709 - 5712
反应条件
sodium hydroxide in water
T=20°C; 18 h;
参考文献
O'Brien, Peter; Childs, Amanda C.; Ensor, Gareth J.; Hill, Cheryl L.; Kirby, Jonathan P.; Dearden, Michael J.; Oxenford, Sally J.; Rosser, Clare M.
Organic Letters, 2003 , vol. 5, # 26 p. 4955 - 4957
参考文献
Shea, Regan G.; Fitzner, Jeffrey N.; Fankhauser, John E.; Spaltenstein, Andreas; Carpino, Philip A.; et al.
Journal of Organic Chemistry, 1986 , vol. 51, # 26 p. 5243 - 5252
反应条件
1: With triethylamine in dichloromethane
T=0 - 20°C; 24 h; Inert atmosphere;
2: Inert atmosphere;
参考文献
Das, Kalpataru; Shibuya, Ryozo; Nakahara, Yasuhito; Germain, Nicolas; Ohshima, Takashi; Mashima, Kazushi
Angewandte Chemie - International Edition, 2012 , vol. 51, # 1 p. 150 - 154
反应条件
N-chloro-succinimide; N-ethyl-N,N-diisopropylamine in methanol
0 deg C up to r.t.;
参考文献
Shea, Regan G.; Fitzner, Jeffrey N.; Fankhauser, John E.; Spaltenstein, Andreas; Carpino, Philip A.; et al.
Journal of Organic Chemistry, 1986 , vol. 51, # 26 p. 5243 - 5252
反应条件
potassium tert-butylate in tetrahydrofuran
参考文献
Xiong, Hui; Frietze, William; Andisik, Donald W.; Ernst, Glen E.; Palmer, William E.; Hinkley, Lindsay; Varnes, Jeffrey G.; Albert, Jeffrey S.; Veale, Chris A.
Tetrahedron Letters, 2010 , vol. 51, # 51 p. 6741 - 6744
反应条件
1: 86 percent / DEAD, PPh3 / tetrahydrofuran / Ambient temperature
2: 82 percent / sodium naphthalenide / 1,2-dimethoxy-ethane / Ambient temperature
View Scheme
参考文献
Henry, James R.; Marcin, Lawrence R.; McIntosh, Matthias C.; Scola, Paul M.; Harris, G. Davis; Weinreb, Steven M.
Tetrahedron Letters, 1989 , vol. 30, # 42 p. 5709 - 5712
反应条件
1: 86 percent / DEAD, PPh3 / tetrahydrofuran / Ambient temperature
2: 82 percent / sodium naphthalenide / 1,2-dimethoxy-ethane / Ambient temperature
View Scheme
参考文献
Henry, James R.; Marcin, Lawrence R.; McIntosh, Matthias C.; Scola, Paul M.; Harris, G. Davis; Weinreb, Steven M.
Tetrahedron Letters, 1989 , vol. 30, # 42 p. 5709 - 5712
反应条件
1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol
2: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 24 h / 20 °C
3: sodium naphthalenide / tetrahydrofuran / 3 h / 20 °C
View Scheme
参考文献
Csatayova, Kristina; Davies, Stephen G.; Lee, James A.; Ling, Kenneth B.; Roberts, Paul M.; Russell, Angela J.; Thomson, James E.
Tetrahedron, 2010 , vol. 66, # 43 p. 8420 - 8440
