4-乙基 2,3,6,7-四氢氮杂卓-1,4-二羧酸-(E)-1-叔丁酯合成路线 （共 4 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in benzene
T=60°C; 1 h;
参考文献
Zhu, Gui-Dong; Gong, Jianchun; Gandhi, Virajkumar B.; Penning, Thomas D.; Giranda, Vincent L.
Patent: US2006/229289 A1, 2006 ;
Location in patent: Page/Page column 22 ;
反应条件
1: sodium tetrahydroborate / water; tetrahydrofuran / 3 h / 0 - 20 °C
2: triethylamine / dichloromethane / 4 h / 0 - 20 °C
3: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 4 h / 20 °C
View Scheme
参考文献
Song, Song; Zhu, Shou-Fei; Pu, Liu-Yang; Zhou, Qi-Lin
Angewandte Chemie - International Edition, 2013 , vol. 52, # 23 p. 6072 - 6075
Angew. Chem., 2013 , vol. 125, # 23 p. 6188 - 6191
反应条件
1: triethylamine / dichloromethane / 4 h / 0 - 20 °C
2: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 4 h / 20 °C
View Scheme
参考文献
Song, Song; Zhu, Shou-Fei; Pu, Liu-Yang; Zhou, Qi-Lin
Angewandte Chemie - International Edition, 2013 , vol. 52, # 23 p. 6072 - 6075
Angew. Chem., 2013 , vol. 125, # 23 p. 6188 - 6191
反应条件
hydrogen; palladium 10 on activated carbon in methanol
参考文献
Zhu, Gui-Dong; Gong, Jianchun; Gandhi, Virajkumar B.; Penning, Thomas D.; Giranda, Vincent L.
Patent: US2006/229289 A1, 2006 ;
Location in patent: Page/Page column 22-23 ;
