1: 97 percent / hydrogen / Pd/C / methanol / 6 h / 760 Torr 2: 90 percent / 2,2,6,6-tetramethyl-1-piperidinyloxy; sodium hypochlorite; sodium chlorite / acetonitrile; aq. phosphate buffer / 6 h / 25 °C / pH 6.8 View Scheme

1.1: 97 percent / hydrogen / Pd/C / methanol / 6 h / 760 Torr 2.1: 90 percent / 2,2,6,6-tetramethyl-1-piperidinyloxy; sodium hypochlorite; sodium chlorite / acetonitrile; aq. phosphate buffer / 6 h / 25 °C / pH 6.8 3.1: ethyl chloroformate; triethylamine / tetrahydrofuran / 0.5 h / 0 °C 3.2: 75 percent / ammonium hydroxide / tetrahydrofuran / 16 h View Scheme

hydrogen; palladium on activated charcoal in methanol P=760 Torr; 6 h;