[4-(吗啉甲基)苯基]甲醇合成路线 （共 3 条）
反应条件
1: With oxalyl dichloride; dimethyl sulfoxide in dichloromethane T=-78 - 20°C; 1 h; 2: With triethylamine in dichloromethane
参考文献
Wong, Norman C.W.; Tucker, Joseph E.L.; Hansen, Henrik C.; Chiacchia, Fabrizio S.; McCaffrey, David
Patent: US2008/188467 A1, 2008 ;
Location in patent: Page/Page column 47 ;
US 20080188467 A1
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=20°C; 2 h;
参考文献
JANSSEN PHARMACEUTICA N.V.; ADDEX PHARMACEUTICALS S.A.
Patent: WO2007/104783 A2, 2007 ;
Location in patent: Page/Page column 48 ;
WO 2007/104783 A2
反应条件
1: 48 h / 20 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / |Reflux
View Scheme
参考文献
RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter Ronald
Patent: US2013/281397 A1, 2013 ;
