1-(2-氯-2-丙烯-1-基)-4-甲氧基苯合成路线 (共 3 条)
反应条件
1: 1-bromo-4-methoxy-benzene With magnesium in tetrahydrofuran
Metallation;
2: 2,3-dichloro-prop-1-ene With CuMe2*SMe2 in tetrahydrofuran
T=0°C; Grignard reaction; 1 h;
参考文献
Hanzawa, Yuji; Kowase, Noboru; Momose, Shu-Ichi; Taguchi, Takeo
Tetrahedron, 1998 , vol. 54, # 38 p. 11387 - 11398
反应条件
iron(II) sulfate in water; dimethyl sulfoxide
0.166667 h;
参考文献
Heinrich, Markus R.; Blank, Olga; Ullrich, Daniela; Kirschstein, Marcel
Journal of Organic Chemistry, 2007 , vol. 72, # 25 p. 9609 - 9616
反应条件
2,3-dichloro-prop-1-ene; magnesium
1.) THF, 2.) THF, rt., 2 h; Yield given. Multistep reaction;
参考文献
Cheng, Jya-Wei; Luo, Fen-Tair
Tetrahedron Letters, 1988 , vol. 29, # 11 p. 1293 - 1294