1.1: DIAD; PPh3 / tetrahydrofuran / -78 °C 2.1: tetrahydrofuran / 2 h 3.1: H2O2; KF; KHCO3 / 60 - 65 °C 4.1: Imidazole 5.1: O3 / propan-1-ol / -70 °C 5.2: Me2S / propan-1-ol 6.1: NaBH4 / propan-1-ol / 0 °C 7.1: I2; Imidazole; PPh3 8.1: dioxane / 2 h / 115 °C 9.1: 76 percent / Bu4NF View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11405916', constants.ctx, '0')">copper(l) iodide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />Grignard reaction;&nbsp;<br /> &nbsp;