4-(2-二正丙基胺乙基)-1,3-二氯-2H-吲哚-2-酮合成路线 （共 19 条）
反应条件
1: sodium hydroxide; water / |Large scale 2: pyridine / |Large scale 3: hydrogenchloride / water / |Large scale View Scheme
参考文献
Organic Process Research and Development, , vol. 2, # 1 p. 3 - 9
反应条件
1: bromine / water / |Irradiation 2: water; methanol / |Acidic conditions; |Large scale 3: anhydrous iron chloride / |Acidic conditions; |Large scale 4: palladium on activated charcoal; sodium hypophosphite hydrate / water; ethyl acetate / |Large scale 5: hydrogenchloride / water / |Large scale View Scheme
参考文献
Organic Process Research and Development, , vol. 2, # 1 p. 3 - 9
反应条件
1: water; methanol / |Acidic conditions; |Large scale 2: anhydrous iron chloride / |Acidic conditions; |Large scale 3: palladium on activated charcoal; sodium hypophosphite hydrate / water; ethyl acetate / |Large scale 4: hydrogenchloride / water / |Large scale View Scheme
参考文献
Organic Process Research and Development, , vol. 2, # 1 p. 3 - 9
反应条件
1: palladium on activated charcoal; sodium hypophosphite hydrate / water; ethyl acetate / |Large scale 2: hydrogenchloride / water / |Large scale View Scheme
参考文献
Organic Process Research and Development, , vol. 2, # 1 p. 3 - 9
反应条件
hydrogenchloride in water
参考文献
Organic Process Research and Development, , vol. 2, # 1 p. 3 - 9
反应条件
ammonia; water T=22 - 25°C; 0.5 h; Purification / work up;
参考文献
SUN PHARMACEUTICAL INDUSTRIES LIMITED
Patent: WO2005/105741 A1, 2005 ;
Location in patent: Page/Page column 8 ;
反应条件
dihydrogen peroxide in dihydrogen peroxide T=80°C; 5 h;
参考文献
Krishnaiah; Murthy, M. Vishnu; Reddy, A. Raghupathi; Kumar, Ramesh; Mukkanti
Journal of the Chinese Chemical Society, 2010 , vol. 57, # 3 A p. 348 - 355
反应条件
dihydrogen peroxide in dihydrogen peroxide
T=80°C; 5 h;
参考文献
Krishnaiah; Murthy, M. Vishnu; Reddy, A. Raghupathi; Kumar, Ramesh; Mukkanti
Journal of the Chinese Chemical Society, 2010 , vol. 57, # 3 A p. 348 - 355
反应条件
dihydrogen peroxide in dihydrogen peroxide
T=80°C; 5 h;
参考文献
Krishnaiah; Murthy, M. Vishnu; Reddy, A. Raghupathi; Kumar, Ramesh; Mukkanti
Journal of the Chinese Chemical Society, 2010 , vol. 57, # 3 A p. 348 - 355
