3-甲基-2-(三氟甲基)吲哚合成路线 （共 9 条）
反应条件
[Ru(tris(2,2'-bipyridyl))3]Cl2·6H2O; N,N,N',N,-tetramethylethylenediamine in acetonitrile T=20°C; Inert atmosphere;
参考文献
Iqbal, Naeem; Choi, Sungkyu; Ko, Euna; Cho, Eun Jin
Tetrahedron Letters, 2012 , vol. 53, # 15 p. 2005 - 2008
反应条件
anhydrous copper acetate in methanol T=20°C; 6 h; Inert atmosphere; regioselective reaction;
参考文献
Shimizu, Ryo; Egami, Hiromichi; Nagi, Tatsuya; Chae, Jungha; Hamashima, Yoshitaka; Sodeoka, Mikiko
Tetrahedron Letters, 2010 , vol. 51, # 45 p. 5947 - 5949
反应条件
anhydrous copper acetate in methanol T=20°C; 12 h;
参考文献
Heterocycles, , vol. 86, # 2 p. 979 - 983
反应条件
trimethylsilyl trifluoromethanesulfonate in dichloromethane T=20°C; 0.0833333 h; Schlenk techniqueInert atmosphere;
参考文献
Heterocycles, , vol. 86, # 2 p. 979 - 983
反应条件
in acetonitrile T=80°C; 24 h; Inert atmosphere;
参考文献
Wiehn, Matthias S.; Vinogradova, Ekaterina V.; Togni, Antonio
Journal of Fluorine Chemistry, 2010 , vol. 131, # 9 p. 951 - 957
反应条件
1: 86 percent / triphenyl phosphine; Et3N / CCl4 / 3 h / Heating 2: 92 percent / N-bromosuccinimide; benzoyl peroxide / CCl4 / Heating 3: 82 percent / magnesium / tetrahydrofuran / 2 h / 0 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 128, # 10 p. 1143 - 1152
反应条件
sodium hydride; dimethyl sulfoxide in tetrahydrofuran T=20°C; 2 h;
参考文献
Wang, Zengxue; Ge, Fenglian; Wan, Wen; Jiang, Haizhen; Hao, Jian
Journal of Fluorine Chemistry, 2007 , vol. 128, # 10 p. 1143 - 1152
反应条件
sodium hydride in tetrahydrofuran; N,N-dimethyl-formamide
参考文献
Ge, Fenglian; Wang, Zengxue; Wan, Wen; Hao, Jian
Synlett, 2007 , # 3 p. 447 - 450
反应条件
1: 93 percent / NaH; Me2SO / various solvent(s); tetrahydrofuran / 2 h / 20 °C
2: 85 percent / N-bromosuccinimide; 2,2'-azobisisobutyronitrile / CCl4 / 5 h / Heating
View Scheme
参考文献
Ge, Fenglian; Wang, Zengxue; Wan, Wen; Hao, Jian
Synlett, 2007 , # 3 p. 447 - 450
