6-苄基-4-氯-5,6,7,8-四氢吡啶并[4,3-d]嘧啶合成路线 （共 3 条）
反应条件
1: With N,N-dimethyl-formamide; trichlorophosphate in acetonitrile T=70°C; 1 h; 2: With sodium hydrogencarbonate in dichloromethane; water T=0°C;
参考文献
RENOVIS, INC.
Patent: WO2008/123963 A1, 2008 ;
Location in patent: Page/Page column 44 ;
WO 2008/123963 A1
反应条件
1: sodium alcoholate / ethanol / 2 h / Reflux 2: trichlorophosphate / N,N-dimethyl-formamide / acetonitrile / 3 h / Reflux View Scheme
参考文献
WO2011/103715 A1, ;
WO 2011/103715 A1
反应条件
1: 2 h / Reflux
2: hydrogen / palladium 10 on activated carbon / methanol / 760.05 Torr
View Scheme
参考文献
RENOVIS, INC.
Patent: WO2008/123963 A1, 2008 ;
WO 2008/123963 A1
