5,6,7,8-四氢咪唑并[1,2-a]吡嗪合成路线 （共 3 条）
反应条件
hydrogen; platinum(IV) oxide in ethanol 1 h;
参考文献
Bonnet, Pierre-Antoine; Sablayrolles, Claire; Chapat, Jean-Pierre
Journal of Chemical Research, Miniprint, 1984 , # 2 p. 468 - 480
反应条件
1: With formic acid; palladium 10 on activated carbon in methanol 5 h; Reflux; 2: With hydrogenchloride in water 2 h; Reflux;
参考文献
US2011/301170 A1, ;
Page/Page column 24 ;
反应条件
triethylamine in dichloromethane T=20°C; 48 h;
参考文献
GLAXO GROUP LIMITED; DEAN, David Kenneth; MUNOZ-MURIEDAS, Jorge; SIME, Mairi; STEADMAN, Jon Graham Anthony; THEWLIS, Rachel Elizabeth Anne; TRANI, Giancarlo; WALL, Ian David; WALTER, Daryl Simon
Patent: WO2010/125101 A1, 2010 ;
Location in patent: Page/Page column 58-59 ;
WO 2010/125101 A1
