4-苯基-4,5,6,7-四氢噻吩并[3,2-c]吡啶合成路线 （共 6 条）
反应条件
1: With triethylamine in ethanol T=20°C; 15 h; 2: With trifluoroacetic acid T=20°C; 72 h; 3: With sodium hydroxide in diethyl ether
参考文献
WO2009/124746 A1, ;
Page/Page column 111 ;
反应条件
sodium tetrahydroborate in ethanol T=20°C; 2 h;
参考文献
Bremner, John B.; Browne, Elaine J.; Chohan, Veronica; Yates, Brian F.
Australian Journal of Chemistry, 1984 , vol. 37, # 5 p. 1043 - 1047
反应条件
trifluoroacetic acid T=20°C; Cyclization; 72 h;
参考文献
Madsen, Peter; Lundbeck, Jane M.; Jakobsen, Palle; Varming, Annemarie R.; Westergaard, Niels
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 9 p. 2277 - 2289
反应条件
water; sodium hydroxide in ethanol 18 h; Inert atmosphereReflux;
参考文献
Kitabatake, Michikazu; Hashimoto, Aki; Saitoh, Toshiaki; Sano, Takehiro; Mohri, Kunihiko; Horiguchi, Yoshie
Heterocycles, 2010 , vol. 81, # 8 p. 1903 - 1921
反应条件
1: toluene / Heating 2: 0.823 g / TFA / 72 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 8, # 9 p. 2277 - 2289
反应条件
1: toluene / Heating 2: 0.823 g / TFA / 72 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 8, # 9 p. 2277 - 2289
