3-(4-羟基丁基)-1H-吲哚-5-甲腈合成路线 （共 2 条）
反应条件
1: base / dichloromethane 2: triethylamine / N,N-dimethyl-formamide / 0.75 h / 77 - 82 °C 3: ammonia / methanol / 25 - 30 °C View Scheme
参考文献
SYMED LABS LIMITED; MOHAN RAO, Dodda; JITHENDER, Aadepu
Patent: WO2014/6637 A2, 2014 ;
反应条件
1.1: AlCl3, aluminium chloride / dichloromethane / 0 - 30 °C
1.2: 0 - 30 °C
1.3: 25 - 30 °C / |Reflux
2.1: hydrogenchloride; sodium cyanoborohydride / acetonitrile; water / 0.33 h / 0 - 30 °C
View Scheme
参考文献
SYMED LABS LIMITED; MOHAN RAO, Dodda; JITHENDER, Aadepu
Patent: WO2014/6637 A2, 2014 ;
